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讲座教授
Reinach, Peter S.

职称:教授

学科:眼科学

研究方向:角膜生理学研究

邮箱:preinach@yahoo.com

个人简介:

厦门大学讲座教授,纽约州立大学(State University of New York)视光学院普通药理学和生物科学教授,哥伦比亚大学(ColumbiaUniversity)眼科客座教授,生理和细胞生物学客座教授。现任纽约 州立大学视光学院生理和药理系主席,美国视觉和眼科研究学会程序计划委员会成员,基础研究评审委员会成员,教工任命和提升委员会成员,屈光手术安全评估委 员会(AIBS)AED CSRA成员,Wakamoto 制药厂科学顾问,NIH小型企业基金评审委员会SBRN-4 成员,美国生物科学研究院专门研究组成员,军队屈光手术评估委员会成员,实验生物和医学进展杂志编辑委员会成员,日本参天制药株式会社科学顾问委员会成 员,日本Wakamoto 制药株式会社科学顾问。长期从事角膜生理学研究,在角膜上皮细胞信号传导通路及离子通道研究方面卓有建树,在国际知名杂志发表论文100余篇。


近期主要论著:
1. Bildin, V.N., Wang, Z., Iserovich, P., Reinach P.S. (2003). p38 MAPK activation during acute hypertonic stress is required for regulatory volume recovery and maintenance of epithelial layer integrity. J. Membr. Biol. 193: 1-13.

2. Yang, H., Ning, G., Wen, Q., Sun, X., Lu, L., Reinach, P.S. (2003). EGF mediated increases in cell growth requires stimulation of store activated channel activity. J. Membr. Biol. 194 47-58.

3. Roderick, C., Wang, L., Reinach, P.S., Lu, L. (2003). Modulation of rabbit corneal epithelial cell proliferation by growth factor-regulated K+ channel activity. J. Membr. Biol. 196: 41-50.

4.Shao, C., Sima, J., Zhang, SX, Jin, J.., Reinach, P., Wang Z, Ma, JX (2004). Suppression of corneal neovascularization by PDGF release from human amniotic membranes. Invest. Ophthalmol. Vis Sci. 45: 1758-1762. 

5. Al-Nakkash, L., Iserovich, P. Coca-Prados, M., Yang, H., Reinach, P.S. (2004). Functional and molecular characterization of a volume-activated chloride channel in rabbit corneal epithelial cells. J. Membr. Biol. 201:41-49.

6. Mergler, S., Pleyer, U., Reinach, P., Bednarz, J. Danowski, H., Engelmann, K., Hartmann, C.,Yousif, T. (2005). EGF suppresses hydrogen peroxide induced Ca2+ influx by inhibiting L-type channel activity in cultured human corneal endothelial cells. Exp. Eye Res. 80:285-293.

7. Wang, L., Reinach, P., Lu, L. (2005). TNFa promotes cell survival through stimulation of K+channel and NFkB activity in corneal epithelial cells. Exp. Cell Res. 311:39-48.

8. Yang, H., Mergler, S., Sun, X., Wang, Z., Lu, L., Bonanno, J.A., Pleyer, U., Reinach, P.S. (2005). TRPC4 knockdown suppresses EGF-induced store operated channel activation and growth in human corneal epithelial cells. J. Biol. Chem. 280: 32230-32237.

9. Capó-Aponte, J., Iserovich, P., Reinach, P.S. (2005). Characterization of regulatory volume behavior by fluorescence quenching in human corneal epithelial cells. J. Membrane Biol. 207: 11-22.

10. Zhuang Z.H., Sun, L., Kong, L., Yu, MC, Reinach, P., Zang Z.W., Ge, B.X. (2006). Drosophila TAB2 is required for immune activation of JNK and NF-Kappa B. Cell Signal. 964-970.

11. Zhang, F., Wen, Q., Mergler, S. Yang, H., Wang, Z. Bildin, V.N., Reinach, P.S. (2006). PKC isoforms-specific enhancement of capacitative calcium entry in human corneal epithelial cells. Invest. Ophthal. Vis. Sci. 47(9): 3989-4000.

12. Lu, J., Lu, Z., Reinach, P.S., Zhang, J., Dai, W., Lu, L., Xu, M. (2006). TGF-beta2 inhibits AKT activation and FGF-2-induced corneal endothelial cell proliferation. Exp. Cell Res. 312(18): 3631-3640.

13. Kitano, A., Saika, S., Yamanaka, O., Reinach, P.S., Ikeda, K., Okada, Y., Shirai, K., Ohnishi, Y. (2006). Genipin suppression of fibrogenic behaviors of the alpha-TN4 lens epithelial cell line. J. Cataract Refract. Surg. 32(10): 1727-1735.

14. Kitano, A., Saika, S., Yamanaka, O., Ikeda, K., Reinach, P.S., Nakajima, Y., Okada, Y., Shirai, K., Ohnishi, Y. (2006). Genipin suppresses subconjuntival fibroblast migration, proliferation and myofibroblast transdifferentiation. Ophthalmic Res. 38(6): 355-60.

15. Du, J., Zhang, F. Capó-Aponte, J.E., Tachadao, S.D., Zhang, J., Yu, F.S., Koziel, H., Sack, R., Reinach, P.S. (2006). AsialoGM1 mediated IL-8 release by human corneal epithelial cells requires coexpression of TLR5. Invest. Ophthal. Vis. Sci. 47(11): 4810-4818.

16. Wang, Z., Yang, H., Tachado, S.D., Capó-Aponte, J.E., Bildin, V.N., Koziel, H., Reinach, P.S. (2006). Phosphatase-induced MAPK crosstalk mediates control of corneal epithelial cell migration. Invest. Ophthal. Vis. Sci. 47(12):5267-5275.


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