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技术人员
刘真

职称:实验师

学科:眼科学

研究方向:眼表干细胞,近视发病机制

邮箱:liuzhen3394@hotmail.com

个人简历:

教育背景:

2000.09-2004.07 河南师范大学生命科学学院,生物技术,本科

2005.09-2008.07 厦门大学生命科学学院,微生物学,硕士

2010.09-2015.07 厦门大学医学院,生理学,博士

 

工作经历:

2004.9-2005.6 河南省正阳县第一高级中学,生物教师

2008.9-2017.7   厦门大学医学院,助理实验师

2017.7-至今  厦门大学医学院,实验师

 

主要研究领域:

主要研究领域为近视的发病机制,包括建立近视的动物模型,在此基础上研究与近视相关的关键信号通路的改变情况,探讨以信号通路为靶点的干预措施对近视发生发展的影响,为近视的治疗提供新的理论依据。


主要学术成果:

全部论文:pubmed

 

代表论文:

1. Qiu F, Liu Z, Zhou Y, He J, Gong S, Bai X, Zeng Y, Liu Z, Ma JX. Sci Rep. 2017 Apr 28;7(1): 1263.Decreased Circulating Levels of Dickkopf-1 in Patients with Exudative Age-related Macular Degeneration.

2. Jeyalatha MV1, Qu Y, Liu Z, Ou S, He X, Bu J, Li S, Reinach PS, Liu Z, Li W. Exp Eye Res. 2017 Oct; 163:29-36. Function of meibomian gland: Contribution of proteins.

3. Liu Z, Qiu F, Li J, Zhu Z, Yang W, Zhou X, An J, Huang F, Wang Q, Reinach PS, Li W, Chen W, Liu Z. PLoS One. 2015 Oct 23;10(10): e0141144. Adenomatous polyposis coli mutation leads to myopia development in mice.

4. Chen W, Liu Z, Tian Q, Niu H, Liu F, Wang X, Xiu Y, Dong N. Eye (Lond). 2016 Nov;30(11):1490-1495. Levator resection with suspensory ligament of the superior fornix suspension for correction of pediatric congenital ptosis with poor levator function.

5. Li J, Li C, Wang G, Liu Z, Chen P, Yang Q, Dong N, Wu H, Liu Z, Li W. Invest Ophthalmol Vis Sci. 2016 Feb 1;57(2): 444-52. APR-246/PRIMA-1Met inhibits and reverses squamous metaplasia in human conjunctival epithelium Conjunctival squamous metaplasia.

6. Zhou T, Zong R, Zhang Z, Zhu C, Pan F, Xiao X, Liu Z, He H, Ma JX, Liu Z, Zhou Y. Invest Ophthalmol Vis Sci. 2012 Jul 27;53(8):5033-43. SERPINA3K Protects against Oxidative Stress via Modulating ROS Generation/Degradation and KEAP1-NRF2 Pathway in the Corneal Epithelium.

7. Liu X, Lin Z, Zhou T, Zong R, He H, Liu Z, Ma JX, Liu Z, Zhou Y. PLoS One, 2011; 6(1): e16712. Anti-angiogenic and Anti-inflammatory Effects of SERPINA3K on Corneal Injury.

8. Qiu F, He J, Zhou Y, Bai X, Wu G, Wang X, Liu Z, Chen Y, Ma JX, Liu Z. EYE (Lond), 2014 Apr;28(4):402-9. Plasma and vitreous fluid levels of Dickkopf-1 in patients with diabetic retinopathy.

9. Xu K, Tao T, Jie J, Lu X, Li X, Mehmood MA, He H, Liu Z, Xiao X, Yang J, Ma JX, Li W, Zhou Y, Liu Z. Mol Vis. 2013;19:604-13. Increased importin 13 activity is associated with the pathogenesis of pterygium.

10. Peng F, Liu Z, Wang L, Shao, Z. The Journal of Applied Microbiology. June 2007, pp. 1603-1611 (9). An oil-degrading bacterium: Rhodococcus erythropolis strain 3C-9 and its biosurfactants.

 

 

 

 

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