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胡皎月助理教授研究团队


 
团队成员:
研究生:孟菊峰,叶立军,赵钟阳
电话:0592-2183761
邮箱:mydear_22000@163.com
 
研究方向:糖尿病性角膜病变
随着糖尿病患者的日益增加,其并发症引起了研究人员的广泛重视,糖尿病眼部并发症(包括糖尿病视网膜病变,糖尿病性白内障)是引起眼盲的重要原因之一。近年来,糖尿病性眼表病变引起了研究者的广泛重视,其表现包括:干眼症、角膜上皮损伤(包括上皮再生迟缓、浅层点状角膜炎、持续性上皮缺损、反复的上皮糜烂、浅层角膜溃疡、丝状角膜炎、大泡形成等)、角膜知觉下降等。氧化应激被认为是导致糖尿病性眼表病变的重要发病机制之一。本课题组致力于研究糖尿病性角膜病变的发病机制及治疗。
 
近期发表的文章:
1、Zhenhao Zhang, Yue Huang, Hui Xie, Juxin Pan, Fanfei Liu, Wensheng Chen, Jiaoyue Hu* (Co-Correspanding), Zuguo Liu*. Benzalkonium Chloride Suppresses Rabbit Corneal Endothelium Intercellular Gap Junction Communication, Plos One, 2014 Oct 9;9(10):e109708.


2、Wensheng Chen*, Nuo Dong, Caihong Huang, Zhenhao Zhang, Jiaoyue Hu, Hui Xie, Juxin Pan, Zuguo Liu*. Corneal Alternations Induced by Topical Application of Commercial Latantoprost, Travoprost and Bimatoprost in Rabbit, Plos One, 2014 Mar 14;9(3):e89205.


3、Wensheng Chen*, Zhenhao Zhang, Jiaoyue Hu, Hui Xie, Juxin Pan, Nuo Dong, Zuguo Liu*. Changes in Rabbit Corneal Innervation Induced by Topical Application of Benzalkonium Chloride, Cornea, 2013;Dec;32(12):1599-606.


4、Jiaoyue Hu#, Zhenhao Zhang#, Hui Xie, Lelei Chen, Yueping Zhou, Juxin Pan, Wensheng Chen*, Zuguo Liu*. Serine protease inhibitor A3K protects rabbit corneal endothelium from barrier function disruption induced by TNF-α, Invest Ophthalmol Vis Sci,2013;Aug 9;54(8):5400-7.


5、Wensheng Chen#, Jiaoyue Hu# (co-first author), Zhenhao Zhang, Lelei Chen, Hui Xie, Nuo Dong, Yongxiong Chen, Zuguo Liu. Localization and Expression of Zonula Occluens-1 in the Rabbit Corneal Epithelium Following Exposure to Benzalkonium Chloride.Plos One, 2012;7(7):e40893.

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